I just completed a complete redesign of my site BonFX.com using Skeleton. Very cool, I must say once again.
From Photoshop to done was only a matter of hours. This was so easy. I had to edit some CSS to handle tweaks to the layout, but most changes were CSS for color and image reference.
One of the pages, a reference for an iPhone app about fonts, was my first 'no widgets' page. I had to ad some page-specific CSS to get rid of certain elements. I'm not sure it was the "right" way to do this, but it worked perfect.
The site is still messy in IE6, but I don't think I care whatsoever.
Do check out the iPhone app page while you are there!